Biological Networks for Cancer Candidate Biomarkers Discovery

Biological Networks for Cancer Candidate Biomarkers Discovery

Due to its extraordinary heterogeneity and complexity, cancer is often proposed as a model case of a systems biology disease or network disease. There is a critical need of effective biomarkers for cancer diagnosis and/or outcome prediction from system level analyses. Methods based on integrating omics data into networks have the potential to revolutionize the identification of cancer biomarker...

Advances in Lipidomics for Cancer Biomarkers Discovery

Lipids play critical functions in cellular survival, proliferation, interaction and death, since they are involved in chemical-energy storage, cellular signaling, cell membranes, and cell-cell interactions. These cellular processes are strongly related to carcinogenesis pathways, particularly to transformation, progression, and metastasis, suggesting the bioactive lipids are mediators of a numb...

Cancer Biomarkers: Analytical Techniques for Discovery

Immunity provides a succinct and straightforward approach to appreciating a complex biological system ridden with intricacies — the immune response. The aim of the text is to guide the readers through the building blocks of the immune system in both health and disease. The early sections of the book detailing the functioning of both the innate and adaptive arm of the immune system provide a fra...

Biomarkers in Breast Cancer Cancer Drug Discovery

Candidate Biomarkers for Genetic and Clinicopathological Diagnosis of Endometrial Cancer

The recent increase in the frequency of endometrial cancer has emphasized the need for accurate diagnosis and improved treatment. The current diagnosis is still based on conventional pathological indicators, such as clinical stage, tumor differentiation, invasion depth and vascular invasion. However, the genetic mechanisms underlying endometrial cancer have gradually been determined, due to dev...